8SWK: Cryo-EM structure of NLRP3 closed hexamer

PDB ID: 8SWKDownload
MMDB ID: 242675
PDB Deposition Date: 2023/5/18
Updated in MMDB: 2024/02
Experimental Method:
electron microscopy
Resolution: 4.32  Å
Source Organism:
Similar Structures:
Biological Unit for 8SWK: hexameric; determined by author
Molecular Components in 8SWK
Label Count Molecule
Proteins (6 molecules)
6
Nacht, LRR and PYD Domains-containing Protein 3
(Gene symbol: NLRP3)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
6
1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea
2
6
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303