8SWE: FGFR2 Kinase Domain Bound to Reversible Inhibitor Cmpd 3

PDB ID: 8SWEDownload
MMDB ID: 242673
PDB Deposition Date: 2023/5/18
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.24  Å
Source Organism:
Similar Structures:
Biological Unit for 8SWE: monomeric; determined by author
Molecular Components in 8SWE
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 2
(Gene symbol: FGFR2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
GLYCEROLGLYCEROL
2
1
GLUTATHIONEGLUTATHIONE
3
1
N-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamideN-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303