8SWA: Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with SAM and PPNP

PDB ID: 8SWADownload
MMDB ID: 238579
PDB Deposition Date: 2023/5/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.999  Å
Source Organism:
Similar Structures:
Biological Unit for 8SWA: dimeric; determined by author and by software (PISA)
Molecular Components in 8SWA
Label Count Molecule
Proteins (2 molecules)
2
S-adenosylmethionine Synthase Isoform Type-1
(Gene symbol: MAT1A)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
(DIPHOSPHONO)AMINOPHOSPHONIC ACID(DIPHOSPHONO)AMINOPHOSPHONIC ACID
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
POTASSIUM IONPOTASSIUM ION
4
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303