8SVT: Crystal structure of pregnane X receptor ligand binding domain in complex with SJPYT-331

PDB ID: 8SVTDownload
MMDB ID: 247025
PDB Deposition Date: 2023/5/17
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Similar Structures:
Biological Unit for 8SVT: dimeric; determined by author and by software (PISA)
Molecular Components in 8SVT
Label Count Molecule
Proteins (2 molecules)
2
Nuclear Receptor Subfamily 1 Group I Member 2, Nuclear Receptor Coactivator 1 Fusion Protein,nuclear Receptor Coactivator 1
(Gene symbol: NR1I2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
methyl 3-{[(1P)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbonyl]amino}-4-{[(3S)-hexan-3-yl]oxy}benzoatemethyl 3-{[(1P)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbonyl]amino}-4-{[(3S)-hexan-3-yl]oxy}benzoate
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303