8SVM: Plasmodium falciparum M17 aminopeptidase bound to MMV1557817

PDB ID: 8SVMDownload
MMDB ID: 245892
PDB Deposition Date: 2023/5/17
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8SVM: hexameric; determined by author and by software (PISA)
Molecular Components in 8SVM
Label Count Molecule
Proteins (6 molecules)
6
Leucine Aminopeptidase
(Gene symbol: PF3D7_1446200)
Molecule annotation
Chemicals and Non-standard biopolymers (45 molecules)
1
6
CARBONATE IONCARBONATE ION
2
12
ZINC IONZINC ION
3
6
N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-3,3-dimethylbutanamideN-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-3,3-dimethylbutanamide
4
15
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
5
6
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303