8SV9: Crystal structure of ULK1 kinase domain with inhibitor MR-2088

PDB ID: 8SV9Download
MMDB ID: 244682
PDB Deposition Date: 2023/5/15
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8SV9: monomeric; determined by author
Molecular Components in 8SV9
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Ulk1
(Gene symbol: ULK1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(4P)-4-[(2P)-2-(1,2,5,6-tetrahydropyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,2,2-trifluoroethyl)thiophene-2-carboxamide(4P)-4-[(2P)-2-(1,2,5,6-tetrahydropyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,2,2-trifluoroethyl)thiophene-2-carboxamide
2
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303