8SSV: Crystal structure of Grp94 N-terminal domain bound to the purine inhibitor PU-H71

PDB ID: 8SSVDownload
MMDB ID: 254545
PDB Deposition Date: 2023/5/9
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.72  Å
Source Organism:
Similar Structures:
Biological Unit for 8SSV: monomeric; determined by author and by software (PISA)
Molecular Components in 8SSV
Label Count Molecule
Protein (1 molecule)
1
Endoplasmin
(Gene symbol: HSP90B1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE
2
3
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
3
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303