8SSP: AurA bound to danusertib and activating monobody Mb1

PDB ID: 8SSPDownload
MMDB ID: 235253
PDB Deposition Date: 2023/5/8
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8SSP: dimeric; determined by author and by software (PISA)
Molecular Components in 8SSP
Label Count Molecule
Proteins (2 molecules)
1
Aurora Kinase a
Molecule annotation
1
MB1
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
SULFATE IONSULFATE ION
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
4
1
PHOSPHATE IONPHOSPHATE ION
5
1
1,3-PROPANDIOL1,3-PROPANDIOL
6
1
N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDEN-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303