8SSB: Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)

PDB ID: 8SSBDownload
MMDB ID: 235250
PDB Deposition Date: 2023/5/8
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.66  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 8SSB: hexameric; determined by author
Molecular Components in 8SSB
Label Count Molecule
Proteins (6 molecules)
4
Glutamate Receptor 2, Voltage-dependent Calcium Channel Gamma-5 Subunit Chimera
Molecule annotation
2
Protein Cornichon Homolog 2
Molecule annotation
Chemicals and Non-standard biopolymers (33 molecules)
1
28
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
2
4
GLUTAMIC ACIDGLUTAMIC ACID
3
1
SPERMIDINESPERMIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303