8SSA: Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)

PDB ID: 8SSADownload
MMDB ID: 235249
PDB Deposition Date: 2023/5/8
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 3.88  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 8SSA: hexameric; determined by author
Molecular Components in 8SSA
Label Count Molecule
Proteins (6 molecules)
4
Glutamate Receptor 2, Voltage-dependent Calcium Channel Gamma-5 Subunit Chimera
Molecule annotation
2
Protein Cornichon Homolog 2
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
12
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
2
4
GLUTAMIC ACIDGLUTAMIC ACID
3
1
SPERMIDINESPERMIDINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303