8SS0: Human sterol 14 alpha-demethylase (CYP51) in complex with the reaction intermediate 14 alpha-aldehyde dihydrolanosterol

PDB ID: 8SS0Download
MMDB ID: 241468
PDB Deposition Date: 2023/5/8
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 8SS0: monomeric; determined by author
Molecular Components in 8SS0
Label Count Molecule
Protein (1 molecule)
1
Lanosterol 14-alpha Demethylase
(Gene symbol: CYP51A1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
3beta-hydroxy-10alpha,13alpha-lanosta-8,24-dien-30-al3beta-hydroxy-10alpha,13alpha-lanosta-8,24-dien-30-al
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303