8SRF: Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state

PDB ID: 8SRFDownload
MMDB ID: 247006
PDB Deposition Date: 2023/5/5
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 2.52  Å
Source Organism:
Similar Structures:
Biological Unit for 8SRF: tetrameric; determined by author
Molecular Components in 8SRF
Label Count Molecule
Proteins (4 molecules)
4
Trpm2 Chanzyme
(Gene symbol: PTSG_05449)
Molecule annotation
Chemicals and Non-standard biopolymers (45 molecules)
1
4
5-O-phosphono-beta-D-ribofuranose5-O-phosphono-beta-D-ribofuranose
2
4
ADENOSINE MONOPHOSPHATEADENOSINE MONOPHOSPHATE
3
4
ADENOSINE-5-DIPHOSPHORIBOSEADENOSINE-5-DIPHOSPHORIBOSE
4
21
MAGNESIUM IONMAGNESIUM ION
5
12
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303