8SR0: CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined

PDB ID: 8SR0Download
MMDB ID: 235240
PDB Deposition Date: 2023/5/5
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.53  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8SR0: hexameric; determined by author
Molecular Components in 8SR0
Label Count Molecule
Proteins (6 molecules)
2
Lymphocyte Activation Gene 3 Protein
Molecule annotation
2
Favezelimab FAB Heavy Chain
Molecule annotation
2
Favezelimab FAB Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303