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8SOK:
Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA
PDB ID:
8SOK
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MMDB ID:
231251
PDB Deposition Date:
2023/4/28
Updated in MMDB:
2023/11
Experimental Method:
electron microscopy
Resolution:
4.1 Å
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
A, E, F
Homo sapiens
B, C, D
Similar Structures:
VAST+
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Biological Unit for 8SOK: hexameric; determined by author
Molecular Components in 8SOK
Label
Count
Molecule
Proteins (5 molecules)
A
1
CST Complex Subunit Ctc1
B
1
CST Complex Subunit Stn1
C
1
CST Complex Subunit Ten1
D
1
Protection of Telomeres Protein 1
E
1
Tpp1
Nucleotide(1 molecule)
F
1
DNA (5'-d(*tp*tp*ap*gp*gp*gp*tp*tp*ap*g)-3')
Chemicals and Non-standard biopolymers (2 molecules)
1
2
ZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303