8SO3: CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3

PDB ID: 8SO3Download
MMDB ID: 235239
PDB Deposition Date: 2023/4/28
Updated in MMDB: 2023/10
Experimental Method:
electron microscopy
Resolution: 3.61  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8SO3: hexameric; determined by author
Molecular Components in 8SO3
Label Count Molecule
Proteins (6 molecules)
2
Lymphocyte Activation Gene 3 Protein
Molecule annotation
2
Favezelimab FAB Heavy Chain
Molecule annotation
2
Favezelimab FAB Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303