8SNM: Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain

PDB ID: 8SNMDownload
MMDB ID: 247624
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.84  Å
Source Organism:
Similar Structures:
Biological Unit for 8SNM: trimeric; determined by author
Molecular Components in 8SNM
Label Count Molecule
Proteins (3 molecules)
1
Inactive Rhomboid Protein 2
(Gene symbol: RHBDF2)
Molecule annotation
1
Disintegrin and Metalloproteinase Domain-containing Protein 17 Propeptide
(Gene symbol: ADAM17)
Molecule annotation
1
Disintegrin and Metalloproteinase Domain-containing Protein 17
(Gene symbol: ADAM17)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303