8SGO: Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus pregnenolone sulfate

PDB ID: 8SGODownload
MMDB ID: 234925
PDB Deposition Date: 2023/4/12
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.65  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 8SGO: nonameric; determined by author
Molecular Components in 8SGO
Label Count Molecule
Proteins (9 molecules)
2
Gamma-aminobutyric Acid Receptor Subunit Beta-2
Molecule annotation
2
Gamma-aminobutyric Acid Receptor Subunit Alpha-1
Molecule annotation
1
Gamma-aminobutyric Acid Receptor Subunit Gamma-2
Molecule annotation
2
Kappa FAB Light Chain
Molecule annotation
2
Igg2b FAB Heavy Chain
Molecule annotation
Chemicals and Non-standard biopolymers (33 molecules)
1
12
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
beta-D-mannopyranosebeta-D-mannopyranose
3
7
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
GAMMA-AMINO-BUTANOIC ACIDGAMMA-AMINO-BUTANOIC ACID
5
6
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
6
1
O-[(R)-[(2S)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-D-serineO-[(R)-[(2S)-2-(hexadecanoyloxy)-3-(octadecanoyloxy)propoxy](hydroxy)phosphoryl]-D-serine
7
1
Pregnenolone sulfatePregnenolone sulfate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303