8SFP: WT CRISPR-Cas12a with the target strand in the RuvC active site

PDB ID: 8SFPDownload
MMDB ID: 249203
PDB Deposition Date: 2023/4/11
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Acidaminococcus sp. BV3L6▼
Similar Structures:
Molecular Components in 8SFP
Label Count Molecule
Protein (1 molecule)
1
Crispr-associated Endonuclease Cas12a
Molecule annotation
Nucleotides(3 molecules)
1
RNA (39-mer)
Molecule annotation
1
DNA (40-mer)
Molecule annotation
1
DNA (5'-d(p*cp*tp*tp*cp*cp*gp*ap*tp*cp*tp*tp*tp*tp*ap*gp*tp*gp*ap*tp*a)-3')
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303