8SE5: NKG2D complexed with inhibitor 14

PDB ID: 8SE5Download
MMDB ID: 236670
PDB Deposition Date: 2023/4/8
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.43  Å
Source Organism:
Similar Structures:
Biological Unit for 8SE5: dimeric; determined by author
Molecular Components in 8SE5
Label Count Molecule
Proteins (2 molecules)
2
Nkg2-d Type II Integral Membrane Protein
(Gene symbol: KLRK1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
N-{(1S)-2-[(1R,5S,6S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamideN-{(1S)-2-[(1R,5S,6S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303