8SD2: Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule fusion inhibitor compound 4

PDB ID: 8SD2Download
MMDB ID: 247908
PDB Deposition Date: 2023/4/6
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.81  Å
Source Organism:
Similar Structures:
Biological Unit for 8SD2: hexameric; determined by author and by software (PISA)
Molecular Components in 8SD2
Label Count Molecule
Proteins (6 molecules)
3
Hemagglutinin HA1 Chain
(Gene symbol: HA)
Molecule annotation
3
Hemagglutinin HA2 Chain
(Gene symbol: HA)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
12
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
NITRATE IONNITRATE ION
3
3
(S~6~S)-N-{3-chloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-sulfonimidoyl fluoride(S~6~S)-N-{3-chloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-sulfonimidoyl fluoride
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303