8SC7: Structure of EGFR in complex with MTX-531

PDB ID: 8SC7Download
MMDB ID: 248189
PDB Deposition Date: 2023/4/5
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.984  Å
Source Organism:
Similar Structures:
Biological Unit for 8SC7: monomeric; determined by author
Molecular Components in 8SC7
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
GLYCEROLGLYCEROL
2
1
CHLORIDE IONCHLORIDE ION
3
1
N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamideN-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303