8S9B: Cryo-EM structure of Nav1.7 with LCM

PDB ID: 8S9BDownload
MMDB ID: 234922
PDB Deposition Date: 2023/3/27
Updated in MMDB: 2023/09
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8S9B: trimeric; determined by author
Molecular Components in 8S9B
Label Count Molecule
Proteins (3 molecules)
1
Sodium Channel Protein Type 9 Subunit Alpha
(Gene symbol: SCN9A)
Molecule annotation
1
Sodium Channel Subunit Beta-1
(Gene symbol: SCN1B)
Molecule annotation
1
Sodium Channel Subunit Beta-2
(Gene symbol: SCN2B)
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
lacosamidelacosamide
3
2
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serineO-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
4
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
5
8
1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
6
3
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303