8S8X: SARS-CoV-2 nsp10-16 methyltransferase in complex with Toyocamycin and m7GpppA-RNA (Cap0-RNA)

PDB ID: 8S8XDownload
MMDB ID: 244355
PDB Deposition Date: 2024/3/7
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 1.99  Å
Source Organism:
Severe acute respiratory syndrome coronavirus 2▼
Similar Structures:
Biological Unit for 8S8X: trimeric; determined by author and by software (PISA)
Molecular Components in 8S8X
Label Count Molecule
Proteins (2 molecules)
1
2'-o-methyltransferase Nsp16
Molecule annotation
1
Non-structural Protein 10
Molecule annotation
Nucleotide(1 molecule)
1
M7gpppa-rna (Cap0-rna)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
2
1
4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
3
1
MAGNESIUM IONMAGNESIUM ION
4
2
ZINC IONZINC ION
5
1
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATEP1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303