8S5W: Cryo-EM structure of fedratinib-bound human SLC19A3 in inward-open state

PDB ID: 8S5WDownload
MMDB ID: 252958
PDB Deposition Date: 2024/2/26
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.05  Å
Source Organism:
Lama glama▼
Similar Structures:
Biological Unit for 8S5W: dimeric; determined by author and by software (PISA)
Molecular Components in 8S5W
Label Count Molecule
Proteins (2 molecules)
1
Nb3.7
Molecule annotation
1
Thiamine Transporter 2
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamideN-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303