8S0R: Cryo-EM structure of CAK modified by covalent inhibitor SY-1365

PDB ID: 8S0RDownload
MMDB ID: 257190
PDB Deposition Date: 2024/2/14
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8S0R: trimeric; determined by author and by software
Molecular Components in 8S0R
Label Count Molecule
Proteins (3 molecules)
1
Cdk-activating Kinase Assembly Factor Mat1
(Gene symbol: MNAT1)
Molecule annotation
1
Cyclin-h
(Gene symbol: CCNH)
Molecule annotation
1
Cyclin-dependent Kinase 7
(Gene symbol: CDK7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
Unknown
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303