8RXR: Crystal structure of VPS34 in complex with inhibitor SB02024

PDB ID: 8RXRDownload
MMDB ID: 244339
PDB Deposition Date: 2024/2/7
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Similar Structures:
Biological Unit for 8RXR: monomeric; determined by author
Molecular Components in 8RXR
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 3-kinase Catalytic Subunit Type 3
(Gene symbol: PIK3C3)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
Unknown
2
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
IMIDAZOLEIMIDAZOLE
4
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303