8RRX: Structure of RyR1 reconstituted into lipid nanodisc in primed state in complex with Ca2+, ATP, caffeine and Nb9657

PDB ID: 8RRXDownload
MMDB ID: 253228
PDB Deposition Date: 2024/1/23
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.1  Å
Source Organism:
Vicugna pacos▼
Similar Structures:
Biological Unit for 8RRX: dodecameric; determined by author and by software
Molecular Components in 8RRX
Label Count Molecule
Proteins (12 molecules)
4
Peptidyl-prolyl Cis-trans Isomerase Fkbp1b
Molecule annotation
4
Ryanodine Receptor 1
Molecule annotation
4
Nanobody 9657
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
4
ZINC IONZINC ION
2
4
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
3
4
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
4
CAFFEINECAFFEINE
5
4
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303