National Center for
Biotechnology Information

8RMM: Structure of heteromeric CALHM2/4 channel in complex with synthetic nanobodies SbC2 and SbC4

PDB ID:

MMDB ID:

248517

PDB Deposition Date:

2024/1/8

Updated in MMDB:

2024/10

Experimental Method:

electron microscopy

Resolution:

3.26 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	L, M, O, P, Q, R, S, T, U, N
Homo sapiens	A, B, C, D, E, F, G, H, I, J, K

Similar Structures:

Biological Unit for 8RMM: 21-meric; determined by author

Molecular Components in 8RMM
Label	Count	Molecule
Proteins (21 molecules)
A B K	3	Calcium Homeostasis Modulator Protein 4
L M U	3	Synthetic Nanobody Sbc4
C D E F G H I J	8	Calcium Homeostasis Modulator Protein 2
O P Q R S T N	7	Synthetic Nanobody Sbc2
Chemicals and Non-standard biopolymers (6 molecules)
1	6	DIUNDECYL PHOSPHATIDYL CHOLINE

* Click molecule labels to explore molecular sequence information.

Citing MMDB