8RMG: Structure of the core ISC complex under turnover conditions (FDX2-bound in distal conformation)

PDB ID: 8RMGDownload
MMDB ID: 256880
PDB Deposition Date: 2024/1/5
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 2.46  Å
Source Organism:
Escherichia coli BL21(DE3)▼
Similar Structures:
Biological Unit for 8RMG: nonameric; determined by author and by software
Molecular Components in 8RMG
Label Count Molecule
Proteins (9 molecules)
2
Isoform Mitochondrial of Cysteine Desulfurase
Molecule annotation
2
LYR Motif-containing Protein 4
Molecule annotation
2
Acyl Carrier Protein
Molecule annotation
2
Isoform 1 of Iron-sulfur Cluster Assembly Enzyme Iscu
Molecule annotation
1
Ferredoxin-2, Mitochondrial
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioateS-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
2
2
FE (II) IONFE (II) ION
3
1
FE2/S2 (INORGANIC) CLUSTERFE2/S2 (INORGANIC) CLUSTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303