8RLN: Crystal structure of human adenosine A2A receptor (construct A2A-PSB2-bRIL) complexed with the partial antagonist LUF5834 at the orthosteric pocket

PDB ID: 8RLNDownload
MMDB ID: 248514
PDB Deposition Date: 2024/1/3
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.43  Å
Source Organism:
Similar Structures:
Biological Unit for 8RLN: monomeric; determined by author and by software (PISA)
Molecular Components in 8RLN
Label Count Molecule
Protein (1 molecule)
1
Adenosine Receptor A2a,soluble Cytochrome B562
(Gene symbol: ADORA2A)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
3
CHOLESTEROLCHOLESTEROL
2
4
OLEIC ACIDOLEIC ACID
3
3
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
4
1
(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
5
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303