8RIY: Human NUDT5 with ibrutinib derivative

PDB ID: 8RIYDownload
MMDB ID: 246138
PDB Deposition Date: 2023/12/19
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.288  Å
Source Organism:
Similar Structures:
Biological Unit for 8RIY: dimeric; determined by author and by software (PISA)
Molecular Components in 8RIY
Label Count Molecule
Proteins (2 molecules)
2
Adp-sugar Pyrophosphatase
(Gene symbol: NUDT5)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303