8RIG: Cryo-EM structure of an MCM helicase single hexamer loaded onto dsDNA

PDB ID: 8RIGDownload
MMDB ID: 257441
PDB Deposition Date: 2023/12/18
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 3.41  Å
Source Organism:
Saccharomyces cerevisiae S288C▼
Similar Structures:
Biological Unit for 8RIG: octameric; determined by author and by software (PISA)
Molecular Components in 8RIG
Label Count Molecule
Proteins (6 molecules)
1
DNA Replication Licensing Factor Mcm2
Molecule annotation
1
DNA Replication Licensing Factor Mcm3
Molecule annotation
1
DNA Replication Licensing Factor Mcm4
Molecule annotation
1
Minichromosome Maintenance Protein 5
Molecule annotation
1
DNA Replication Licensing Factor Mcm6
Molecule annotation
1
DNA Replication Licensing Factor Mcm7
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*gp*cp*ap*tp*gp*cp*ap*tp*gp*cp*ap*tp*gp*cp*ap*tp*gp*cp*ap*t)-3')
Molecule annotation
1
DNA (5'-d(p*ap*tp*gp*cp*ap*tp*gp*cp*ap*tp*gp*cp*ap*tp*gp*cp*ap*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
6
MAGNESIUM IONMAGNESIUM ION
3
5
ZINC IONZINC ION
4
4
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303