8RIF: Cryo-EM structure of the MCM double hexamer loaded onto dsDNA

PDB ID: 8RIFDownload
MMDB ID: 257440
PDB Deposition Date: 2023/12/18
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 8RIF: 14-meric; determined by author and by software
Molecular Components in 8RIF
Label Count Molecule
Proteins (12 molecules)
2
DNA Replication Licensing Factor Mcm2
Molecule annotation
2
DNA Replication Licensing Factor Mcm3
Molecule annotation
2
DNA Replication Licensing Factor Mcm4
Molecule annotation
2
Minichromosome Maintenance Protein 5
Molecule annotation
2
DNA Replication Licensing Factor Mcm6
Molecule annotation
2
DNA Replication Licensing Factor Mcm7
Molecule annotation
Nucleotides(2 molecules)
1
DNA (53-mer)
Molecule annotation
1
DNA (53-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (26 molecules)
1
2
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
8
MAGNESIUM IONMAGNESIUM ION
3
10
ZINC IONZINC ION
4
6
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303