8RB6: Structure of Aldo-Keto Reductase 1C3 (AKR1C3) in complex with an inhibitor M689, with the 3-hydroxy-benzoisoxazole moiety. Resolution 2.0A

PDB ID: 8RB6Download
MMDB ID: 243717
PDB Deposition Date: 2023/12/3
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 8RB6: monomeric; determined by author
Molecular Components in 8RB6
Label Count Molecule
Protein (1 molecule)
1
Aldo-keto Reductase Family 1 Member C3
(Gene symbol: AKR1C3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
4-[[4-(3-hydroxyphenyl)phenyl]amino]-1,2-benzoxazol-3-ol4-[[4-(3-hydroxyphenyl)phenyl]amino]-1,2-benzoxazol-3-ol
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303