8R9S: A soakable crystal form of human CDK7 in complex with AMP-PNP

PDB ID: 8R9SDownload
MMDB ID: 247608
PDB Deposition Date: 2023/11/30
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 2.78  Å
Source Organism:
Similar Structures:
Biological Unit for 8R9S: monomeric; determined by author
Molecular Components in 8R9S
Label Count Molecule
Protein (1 molecule)
1
Cyclin-dependent Kinase 7
(Gene symbol: CDK7)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
3
1
[(3S)-1-[4-(dimethylamino)butanoyl]pyrrolidin-3-yl] 4-[(5-methyl-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-7-yl)amino]piperidine-1-carboxylate[(3S)-1-[4-(dimethylamino)butanoyl]pyrrolidin-3-yl] 4-[(5-methyl-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-7-yl)amino]piperidine-1-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303