8R8R: Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc)

PDB ID: 8R8RDownload
MMDB ID: 245218
PDB Deposition Date: 2023/11/29
Updated in MMDB: 2025/07
Experimental Method:
electron microscopy
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 8R8R: pentameric; determined by author
Molecular Components in 8R8R
Label Count Molecule
Proteins (4 molecules)
1
Cleavage and Polyadenylation Specificity Factor Subunit 1
(Gene symbol: CPSF1)
Molecule annotation
1
Pre-mrna 3' END Processing Protein Wdr33
(Gene symbol: WDR33)
Molecule annotation
1
Cleavage and Polyadenylation Specificity Factor Subunit 4
(Gene symbol: CPSF4)
Molecule annotation
1
Cdna Flj50397, Highly Similar to Poly(a) Polymerase Alpha
Molecule annotation
Nucleotide(1 molecule)
1
RNA (5'-r(p*ap*ap*up*ap*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303