8R8E: DYRK1a in Complex with 2-Cyclopentyl-7-iodo-1H-indole-3-carbonitrile

PDB ID: 8R8EDownload
MMDB ID: 252637
PDB Deposition Date: 2023/11/29
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.22  Å
Source Organism:
Similar Structures:
Biological Unit for 8R8E: monomeric; determined by author
Molecular Components in 8R8E
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
1
2-cyclopentyl-7-iodanyl-1~{H}-indole-3-carbonitrile2-cyclopentyl-7-iodanyl-1~{H}-indole-3-carbonitrile
2
2
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
3
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
4
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
5
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
5
GLYCEROLGLYCEROL
7
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
8
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303