8R7E: MutSbeta bound to compound CHDI-00898647 in the canonical DNA-mismatch bound form

PDB ID: 8R7EDownload
MMDB ID: 255641
PDB Deposition Date: 2023/11/24
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.783  Å
Source Organism:
Similar Structures:
Biological Unit for 8R7E: tetrameric; determined by author and by software (PISA)
Molecular Components in 8R7E
Label Count Molecule
Proteins (2 molecules)
1
DNA Mismatch Repair Protein Msh2
(Gene symbol: MSH2)
Molecule annotation
1
DNA Mismatch Repair Protein Msh3
(Gene symbol: MSH3)
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*tp*cp*tp*ap*tp*cp*tp*gp*ap*ap*gp*cp*cp*gp*ap*tp*cp*gp*ap*tp*gp*g)-3')
Molecule annotation
1
DNA (5'-d(*cp*ap*tp*cp*gp*ap*tp*cp*gp*cp*ap*gp*cp*tp*tp*cp*ap*gp*ap*tp*ap*gp*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
CHLORIDE IONCHLORIDE ION
4
1
AbivertinibAbivertinib
5
3
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303