8R7B: SARS-CoV-2 NSP14 in complex with SAH and TDI-015051

PDB ID: 8R7BDownload
MMDB ID: 253893
PDB Deposition Date: 2023/11/24
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.18  Å
Source Organism:
Similar Structures:
Biological Unit for 8R7B: monomeric; determined by author
Molecular Components in 8R7B
Label Count Molecule
Protein (1 molecule)
1
Guanine-n7 Methyltransferase Nsp14
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
ZINC IONZINC ION
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
IMIDAZOLEIMIDAZOLE
5
1
N-[(5-fluoranyl-1-benzofuran-4-yl)methyl]-1,5-dimethyl-4-(1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-ylsulfonyl)pyrrole-2-carboxamideN-[(5-fluoranyl-1-benzofuran-4-yl)methyl]-1,5-dimethyl-4-(1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-ylsulfonyl)pyrrole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303