8R5R: Structure of apo TDO with a bound inhibitor

PDB ID: 8R5RDownload
MMDB ID: 241438
PDB Deposition Date: 2023/11/17
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 3.078  Å
Source Organism:
Similar Structures:
Biological Unit for 8R5R: tetrameric; determined by author
Molecular Components in 8R5R
Label Count Molecule
Proteins (4 molecules)
4
Tryptophan 2,3-dioxygenase
(Gene symbol: TDO2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
3-chloranyl-~{N}-[(1~{S})-1-(6-chloranylpyridin-3-yl)-2-phenyl-ethyl]aniline3-chloranyl-~{N}-[(1~{S})-1-(6-chloranylpyridin-3-yl)-2-phenyl-ethyl]aniline
2
4
alpha-methyl-L-tryptophanalpha-methyl-L-tryptophan
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303