8R5C: Crystal structure of human TRIM7 PRYSPRY domain bound to (2-(1-oxoisoindolin-2-yl)-3-phenylpropanoyl)-L-glutamine

PDB ID: 8R5CDownload
MMDB ID: 241435
PDB Deposition Date: 2023/11/16
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 8R5C: monomeric; determined by author
Molecular Components in 8R5C
Label Count Molecule
Protein (1 molecule)
1
E3 Ubiquitin-protein Ligase Trim7
(Gene symbol: TRIM7)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
(2~{S})-5-azanyl-5-oxidanylidene-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]pentanoic acid(2~{S})-5-azanyl-5-oxidanylidene-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]pentanoic acid
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
S,R MESO-TARTARIC ACIDS,R MESO-TARTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303