8R4V: Structure of Salt-inducible kinase 3 in complex with inhibitor

PDB ID: 8R4VDownload
MMDB ID: 244660
PDB Deposition Date: 2023/11/14
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8R4V: monomeric; determined by author
Molecular Components in 8R4V
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Sik3
(Gene symbol: SIK3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]urea1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303