8R4O: Salt inducible kinase 3 in complex with inhibitor

PDB ID: 8R4ODownload
MMDB ID: 244657
PDB Deposition Date: 2023/11/14
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.725  Å
Source Organism:
Similar Structures:
Biological Unit for 8R4O: dimeric; determined by author
Molecular Components in 8R4O
Label Count Molecule
Proteins (2 molecules)
1
Serine/threonine-protein Kinase Sik3
(Gene symbol: SIK3)
Molecule annotation
1
Scfvh1
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
2-[bis(fluoranyl)methoxy]-4-[6-(2-cyanopropan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]-~{N}-[(1~{R},2~{S})-2-fluoranylcyclopropyl]-6-methoxy-benzamide2-[bis(fluoranyl)methoxy]-4-[6-(2-cyanopropan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]-~{N}-[(1~{R},2~{S})-2-fluoranylcyclopropyl]-6-methoxy-benzamide
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303