8R42: Structure of CHI3L1 in complex with inhibititor 2

PDB ID: 8R42Download
MMDB ID: 244010
PDB Deposition Date: 2023/11/10
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.32  Å
Source Organism:
Similar Structures:
Biological Unit for 8R42: dimeric; determined by author and by software
Molecular Components in 8R42
Label Count Molecule
Proteins (2 molecules)
2
Chitinase-3-like Protein 1
(Gene symbol: CHI3L1)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-[4-[(2~{R})-2-[(4-chlorophenyl)methyl]pyrrolidin-1-yl]piperidin-1-yl]pyridine2-[4-[(2~{R})-2-[(4-chlorophenyl)methyl]pyrrolidin-1-yl]piperidin-1-yl]pyridine
3
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
SULFATE IONSULFATE ION
5
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303