8R41: Structure of CHI3L1 in complex with inhibitor 1

PDB ID: 8R41Download
MMDB ID: 244009
PDB Deposition Date: 2023/11/10
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 8R41: monomeric; determined by author
Molecular Components in 8R41
Label Count Molecule
Protein (1 molecule)
1
Chitinase-3-like Protein 1
(Gene symbol: CHI3L1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
~{N}-[2-(4-bromophenyl)ethyl]-~{N}-(2-methoxyethyl)-1-(1,3-thiazol-2-yl)piperidin-4-amine~{N}-[2-(4-bromophenyl)ethyl]-~{N}-(2-methoxyethyl)-1-(1,3-thiazol-2-yl)piperidin-4-amine
3
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
BROMIDE IONBROMIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303