8R3U: Crystal structure of DHPS in complex with an inhibitor

PDB ID: 8R3UDownload
MMDB ID: 255208
PDB Deposition Date: 2023/11/10
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 8R3U: tetrameric; determined by author
Molecular Components in 8R3U
Label Count Molecule
Proteins (4 molecules)
4
Deoxyhypusine Synthase
(Gene symbol: DHPS)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
4
2-[(2~{R})-1-azanyl-4-methyl-pentan-2-yl]-5-pyridin-3-yl-isoquinolin-1-one2-[(2~{R})-1-azanyl-4-methyl-pentan-2-yl]-5-pyridin-3-yl-isoquinolin-1-one
2
18
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303