8R2A: CpKRS complexed with lysine and an inhibitor

PDB ID: 8R2ADownload
MMDB ID: 254107
PDB Deposition Date: 2023/11/3
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8R2A: dimeric; determined by author and by software (PISA)
Molecular Components in 8R2A
Label Count Molecule
Proteins (2 molecules)
2
Lysine--trna Ligase
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
LYSINELYSINE
2
2
2-azanyl-4-(trifluoromethyl)-6-[[(1~{R},3~{S})-3-(trifluoromethyl)cyclohexyl]methyl]-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one2-azanyl-4-(trifluoromethyl)-6-[[(1~{R},3~{S})-3-(trifluoromethyl)cyclohexyl]methyl]-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one
3
1
GLYCEROLGLYCEROL
4
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303