8QZQ: Single particle cryo-EM co-structure of E. coli AcrB with bound BDM91531 inhibitor

PDB ID: 8QZQDownload
MMDB ID: 254515
PDB Deposition Date: 2023/10/29
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.23  Å
Source Organism:
Similar Structures:
Biological Unit for 8QZQ: trimeric; determined by author
Molecular Components in 8QZQ
Label Count Molecule
Proteins (3 molecules)
3
Multidrug Efflux Pump Subunit Acrb
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
[3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine[3-(3-chloranyl-2-piperazin-1-yl-quinolin-6-yl)phenyl]methanamine
2
1
[(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl] tricosanoate[(2~{R})-1-[[(2~{R})-2,3-bis(oxidanyl)propoxy]-oxidanyl-phosphoryl]oxy-3-undecanoyloxy-propan-2-yl] tricosanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303