8QXL: Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed

PDB ID: 8QXLDownload
MMDB ID: 246985
PDB Deposition Date: 2023/10/24
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 2.82  Å
Source Organism:
Similar Structures:
Biological Unit for 8QXL: tetrameric; determined by author and by software
Molecular Components in 8QXL
Label Count Molecule
Proteins (4 molecules)
4
Deoxynucleoside Triphosphate Triphosphohydrolase Samhd1
(Gene symbol: SAMHD1)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
4
FE (III) IONFE (III) ION
3
10
MAGNESIUM IONMAGNESIUM ION
4
2
2'-DEOXYCYTIDINE2'-DEOXYCYTIDINE
5
2
TRIPHOSPHATETRIPHOSPHATE
6
4
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
7
2
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303