8QXJ: Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp

PDB ID: 8QXJDownload
MMDB ID: 246983
PDB Deposition Date: 2023/10/24
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 2.65  Å
Source Organism:
Similar Structures:
Biological Unit for 8QXJ: tetrameric; determined by author and by software
Molecular Components in 8QXJ
Label Count Molecule
Proteins (4 molecules)
4
Deoxynucleoside Triphosphate Triphosphohydrolase Samhd1
(Gene symbol: SAMHD1)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
8
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine
2
4
FE (III) IONFE (III) ION
3
12
MAGNESIUM IONMAGNESIUM ION
4
4
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303